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The CAARMS: Assessing Young People at Ultra High Risk of Psychosis. This manual is aimed at mental health professionals working with young people who. Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental . To assess predictive validity, the CAARMS-defined UHR criteria were. Comprehensive Assessment of At-Risk Mental States (CAARMS; the CAARMS before assessing psychosis risk, either through their headspace centre or.

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Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States.

To elucidate this difference we conducted a qualitative analysis of the medical records of these 14 subjects. Avoiding the use of external and non-help-seeking control groups who do not reflect the clinical composition of people caafms assessed in high risk is essential to properly compare the diagnostic abilities of the two instruments.

There is also recent meta-analytical evidence indicating that samples referred to high-risk services are highly heterogeneous and that their actual composition may reflect the type of outreach campaigns adopted [ 3637 ]. This is the first psycnosis study addressing comparability of the two psychometric instruments most frequently used to interview subjects seeking help from high-risk services for psychosis.

These findings however psycohsis be influenced by the type of recruitment strategies adopted by the high-risk services. Their pivotal work resulted in the formulation of three UHR criteria: Referrals for both services are accepted from multiple sources including general practitioners, other mental health services, school and college counselors, relatives, and self-referrals [ 18 ].

However, their operationalization differs [ 10 ], with substantial changes over different versions of the instruments [ 10 ]. Similarly, differences on psychosis threshold in the Perceptual Abnormalities subscale i.

Our third aim was to develop a pragmatic algorithm to convert individual cases across the two instruments, to implement it in an automated conversion package CONVERTand to validate it in an independent UHR sample.

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The kappa remained substantial when it was estimated psycohsis the subset of subjects rated by caaarms raters overall agreement Also, operationalization differences in APS onset criteria did not impact the overall consistency of the diagnostic interview for APS across the two instruments.

Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States.

Woods, The Psychosis-Risk Syndrome: Psychometric uncertainty may significantly impact the development of future large-scale UHR multicentre studies, by amplifying heterogeneity across individual sites. External validation was performed in an independent sample assessed for suspicion of UHR symptoms at the Seoul Youth Clinic see paychosis 5. We further converted the severity and frequency of symptoms by employing a linking method, using equate 2.

The study samples were designed to reflect at-risk populations as they are encountered in day-to-day practice: Finally, in a recent meta-analysis we specifically confirmed that, in help-seeking samples, the two instruments share similar excellent prognostic accuracy in ruling out psychosis risk, with no significant differences [ 26 ].

However, type of recruitment strategies may have inflated the observed agreement and future studies should repeat these analyses in high-risk services adopting different outreach campaigns. The resulting overall weight of similarities and differences between the two instruments on UHR identification is unknown.

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The primary aim of the study was investigated by comparing the diagnostic outcomes i. First, the two instruments show similar psychometric parameters, such as excellent reliability properties overall IRR agreement for the SIPS 0. The IRRs for each subscale were in the excellent range: A software engineer JL then implemented the conversion algorithm in an automated package.

CAMEO was started in and it is an early intervention in psychosis service which offers management for UHR people aged 17—35 in Cambridgeshire, Csarms, and provides initial assessments to those under The ROC caaarms serves as a global measure of test performance and values in the range of 0. Our results are thus highly relevant to permit overall meaningful comparisons of clinical, neurobiological, neurocognitive, and cost-effectiveness UHR studies worldwide, with potential beneficial impact for ongoing large-scale multicentre UHR projects such as the PRONIA http: This method is detailed in eMethod 2.


However, assessing subjects referred for suspicion of UHR symptoms at the time of the first contacts with high-risk services who may be already psychotic or eventually deemed not at risk of psychosis with independent raters poses severe logistic difficulties for the patients. This algorithm has been implemented in the CONVERT tool, which has been made freely available for the use of future researchers psyfhosis clinicians and externally validated in an independent sample.

Subjects are recruited from Seoul National University Hospital and other psychiatric clinics and public mental health centers or they can contact the clinic by telephone or an Internet homepage. Of the subjects, 82 were females Furthermore, we only included subjects who were directly assessed with both psychometric instruments during face-to-face interviews, excluding those who declined the full assessment or who were unable to complete it.

However, we also found some sources of disagreement, in particular, with respect to the diagnosis of BLIPS cwarms.

It may also paradoxically create additional biases because the most severe patients may be more likely to decline lengthy assessments. Our secondary aim was to qualitatively investigate potential discrepancies across the two instruments and to provide equipercentile-linking comparisons. The prevalence and bias adjusted kappa was 0. The pragmatic algorithm to convert individual cases across the SIPS 5. Gonen, Single Case Research: